Risk Factors Linked to Non-Hodgkin Lymphoma
- Age, gender, race, and family history are well-established risk factors for this cancer
- Radiation exposure might slightly increase the risk in people younger than 18
- Studies haven’t proven a link between weed killer and non-Hodgkin lymphoma
The Radiation Link
Radiation is one risk that has been linked to non-Hodgkin lymphoma in studies. People who’ve been treated with radiation therapy for other forms of cancer are more likely to develop lymphoma later on. Repeated exposure to radiation during imaging tests such as CT scans could also be a risk, but mainly for younger people.
Read MoreCan Weed Killer Cause Cancer?
A chemical called glyphosphate is the active ingredient in Roundup and certain other weed killers. In 2015, the World Health Organization classified glyphosphate as “possibly carcinogenic to humans.” Juries have since awarded millions of dollars to people who claimed these products caused their cancer. In 2019, a jury in California awarded $80 million to a man who said Roundup caused his non-Hodgkin lymphoma. Related: Does Weed Killer Cause Cancer? We Don't Know, But Buy Organic to Be SafeStudies have been investigating whether weedkillers cause non-Hodgkin lymphoma, but so far they haven’t proven a link. “The way we need to study that is through a large epidemiologic study looking at people who were exposed versus people who weren’t and whether or not they developed lymphoma. But that data currently doesn’t exist,” Dr. Chong says.
Other Non-Hodgkin Lymphoma Risks
A few other non-Hodgkin lymphoma risk factors have more science to back them up, including:
Age. Non-Hodgkin lymphoma usually starts in people who are in their 60s and older, although it’s possible for younger people to get diagnosed. Hodgkin lymphoma, on the other hand, is more common in younger people.
Gender. Most types of non-Hodgkin lymphoma are slightly more likely to affect men than women.
Race and ethnicity. In the United States, this cancer is more common in white people than in Black or Asian Americans.
Family history. Having a close family member with non-Hodgkin lymphoma — a parent, brother or sister, or child — could make you more likely to develop it, too.
Infections. Both bacterial and viral infections have been linked to this cancer, including the Epstein-Barr virus and HIV.
Autoimmune diseases. In people with diseases such as lupus or Sjögren syndrome, the overactive immune response may cause lymphocytes to multiply faster than normal.
A weakened immune system. People whose immune system has been weakened by anti-rejection drugs after an organ transplant or by HIV/AIDS have a higher risk for non-Hodgkin lymphoma.
Remember that, even if you do have one of these risks, there’s only a very small chance that you’ll ever develop non-Hodgkin lymphoma. And it is possible to get lymphoma, even if you don’t have a single risk for it.
What Can You Do?
When it comes to factors such as your genes, age, or gender, there isn’t much you can do to change them. Yet you can reduce your exposure to chemicals, including weed killers and pesticides.
Try to avoid using these products at home, and if you do need to use them at work, take precautions. “Wear whatever protective equipment you have available … thick gloves, a mask, goggles when spraying,” says Dr. Chong. “I think that that’s certainly healthier overall, even if we haven’t directly shown that that increases your risk of developing lymphoma.”
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