The Importance of Colorectal Cancer Screenings
- Actor James Van Der Beek, known for his iconic role as Dawson Leery on The WB’s ‘Dawson’s Creek’, has been diagnosed with colorectal cancer at 47 years old.
- It’s unclear what stage cancer Van Der Beek was diagnosed with or what type of treatment he will be undergoing, but his story is a reminder on the importance of colorectal cancer screenings and early detection.
- Colon cancers start out as a polyp, or small growth, in the colon that causes no symptoms. Although polyps can’t be felt, they can be picked up by screening tests before they cause a problem. It takes up to 10 years for a colon polyp to become a full-blown cancer, which gives doctors time to remove the polyp before it causes a problem.
- The U.S. Preventive Services Task Force recommends state colon cancer screenings should begin at 45-years-old. This is in response to a rise in colon cancer diagnoses in younger adults. In the past, the disease had predominantly been found in adults 50-years or older, but for those predisposed to get it at a younger age, these new guidelines could potentially help catch it at an earlier stage.
- The best and most complete way of screening is a colonoscopy every 10 years. In general, you should get your first colonoscopy at age 45 but the guidelines differ depending on your risk category.
- Dr. Heather Yeo, a colorectal surgeon and surgical oncologist at Weill Cornell Medicine and New York-Presbyterian, previously told SurvivorNet, “Colon cancer is considered a silent and deadly killer. What happens is people often don’t know that they have colon cancer. They don’t have any symptoms. That’s why we screen for colon cancer in the United States.”
Colorectal cancer cases have been rising among younger people across the country, and the United States Preventive Services Task Force recently updated its colorectal cancer screening recommendations to begin at age 45 instead of 50.
Read More“Apologies to all the people in my life who I’d planned on telling myself. Nothing about this process has occurred on my preferred timeline… But we roll with it, taking each surprise as a signpost, pointing us toward a greater destiny than we would have discovered without divine intervention.”
Van Der Beek concluded, “Please know that my family and I deeply appreciate all the love and support. More to come…”
RELATED: What You Need to Know About Colonoscopies
His post comes as People magazine announced the news with him telling the news outlet, “I have colorectal cancer. I’ve been privately dealing with this diagnosis and have been taking steps to resolve it, with the support of my incredible family.
“There’s reason for optimism, and I’m feeling good.”
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As we await more details into what stage cancer Van Der Beek was diagnosed with, or the treatment plan he will undergo, we certainly do admire his ability to open up about such a private matter and keep his fans informed. And one thing is for sure—he has his family by his side for support.
Van Der Beek recently celebrated 14 years with his wife Kimberly, with a sweet social media post reading, “14 years… I always say it doesn’t feel like that long. You always say it does. Nothing could have prepared us for this past year – except perhaps the previous 12.
“Thank you for being the most incredible partner. You’ve broken me open in spots I didn’t even know were locked, and taught me how to receive more love than I thought possible. In the past, I feel like you’ve always set the pace for our co-evolution, but this year, as I’ve gone through my own radical transformation, you’ve tirelessly put in the work and somehow managed to match it.”
He concluded by thanking her for her “courage, strength, vulnerability, and tenderness,” added, “I’m thrilled and grateful to get to do this life with you. And now… let’s have a laugh. I love you beyond. Happy anniversary. Thank you for being in the world.”
The loving couple are parents to their six children: Olivia, Joshua, Annabel, Emilia, Gwendolyn and Jeremiah—all whom are often pictured in photographs on Van Der Beek’s Instagram page.
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Understanding Colon Cancer
Colorectal cancer happens when polyps are not removed and become cancerous. It can take up to 10 years for a colon polyp to become cancerous, according to SurvivorNet experts.
“We know that colon cancers can be prevented when polyps are found early,” Dr. Heather Yeo, a surgical oncologist who specializes in colorectal cancers at Weill Cornell Medicine, told SurvivorNet.
“Lowering the screening age helps somewhat with this, but access to care is a real problem,” Dr. Yeo added.
Expert Resources for Colon Cancer Screening
- Colon Cancer Screening is Extremely Important; Guidelines Now Say to Start at Age 45 if There Is No Family History
- Colon Cancer Screening Options And Genetics: Myth Busting With Dr. Heather Yeo
- Everything You Need to Know About Colorectal Cancer Screenings
- Replacing a Colonoscopy With At-Home Tests Sounds Good, But Doesn’t Necessarily Work
- Colon Cancer Diagnosis: What Happens After the Colonoscopy
- Colon Cancer: Introduction to Prevention and Screening
- Screening for Colon Cancer At Home: The New Approval for Younger People — Still Not a Substitute for a Colonoscopy
Dr. Zuri Murrell, a colorectal cancer surgeon and Director of the Cedars-Sinai Colorectal Cancer Center, previously explained the colonoscopy procedure to SurvivorNet.
“When we see a polyp, we actually physically take the polyp out through the colonoscope,” he explained.
“What does that mean? That means we basically put a wire through with a little bit of a flange at the end, and we pull the polyp out. Now, note there is no pain with that. Inside the colon, there are no pain fibers. So, there’s no pain,” Dr. Murrell added.
The advantage of a colonoscopy is that your doctor can remove any polyps found during the test. Many colon cancers can be caught on colonoscopy before they develop or when the polyps are small enough to be removed without surgery.
Looking for Polyps During Colonoscopy
The American Gastrointestinal Association lowered the recommended initial age for a colorectal screening from 50 to 45.
The U.S. Preventive Services Task Force recommends guidelines that state colon cancer screenings should begin at 45 years old. This is in response to the increase we see in colon cancer diagnoses in younger adults.
However, many insurance companies still do not cover the cost of screenings for those under 50. In the past, the disease had predominantly been found in adults 50 years or older, but for those predisposed to getting it at a younger age, these new guidelines could help catch it earlier.
Colon Cancer: A Silent Killer
Dr. Heather Yeo, a colorectal surgeon and surgical oncologist at Weill Cornell Medicine and New York-Presbyterian, previously told SurvivorNet, “Colon cancer is considered a silent and deadly killer.
RELATED: How Does a Colon Polyp Turn Into Cancer?
“What happens is people often don’t know that they have colon cancer. They don’t have any symptoms. That’s why we screen for colon cancer in the United States.”
The Rate of Colon Cancer is Increasing in Those Under 50
“You should be screened for colon cancer, even if you have no family history. Once you have your initial screening colonoscopy, if there are no polyps and you have no high-risk factors, usually once every 10 years is fine,” she advises.
“Colon cancer is a slowly progressing cancer. If you have any family history of colon cancer, you should be screened about 10 years before your family member had colon cancer. So if you have a family member that was 53, you should be screened at 43.”
Colon Cancer Appearing More in Younger People
Although the average age people are diagnosed with colon cancer is 68 for men and 72 for women, according to the American Cancer Society, the National Cancer Institute reports that since the 1990s, colorectal cancer cases have been rising among adults younger than 50.
Research published in CA: A Cancer Journal for Clinicians found the proportion of cases in people younger than 55 years old increased from 11% in 1995 to 20% in 2019.
“We know rates are increasing in young people, but it’s alarming to see how rapidly the whole patient population is shifting younger, despite shrinking numbers in the overall population,” cancer epidemiologist and lead study author Rebecca Siegel said.
Researchers are still trying to determine why younger people are being diagnosed in greater numbers. Some experts point to risk factors, which include obesity, physical inactivity, and smoking, as a possible explanation for the increase.
“We don’t know for sure why we are seeing earlier onset and (cancer mortality) from colon cancer,” Dr. Yeo told SurvivorNet. It is likely a combination of factors, including diet and genetics as well as access to care and some environmental factors.”
Dr. Paul Oberstein Explains Common Colon Cancer Symptoms
What Increases Your Risk for Developing Colon Cancer?
For some people, certain risk factors can influence their risk of getting colon cancer. They include the following:
- Are older. About 90% of cases are in people aged 50 or older, according to the U.S. Centers for Disease Control & Prevention (CDC). Yet it is possible to get this cancer earlier in life.
- Have inflammatory bowel disease. Crohn’s disease or ulcerative colitis can, over time, cause cells in your intestines to turn cancerous.
- Have a family history of this cancer. Just under one-third of people who get colon cancer have family members with the disease.
- Have a gene mutation. About 5% of colorectal cancers are caused by an inherited genetic mutation that causes syndromes such as familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer (Lynch syndrome).
- Don’t exercise very often. Staying active can lower your risk.
- Eat a diet that’s high in meat. Regularly eating red meats like burgers and steaks, and processed meats such as hot dogs and bacon might put you at higher risk. Eating more fruits, vegetables, and whole grains instead might lower your risk.
- You are overweight or obese. Having too much weight increases your risk of both getting colon cancer and dying from it.
- Drink a lot of alcohol. Limiting alcohol to one drink daily for women and two drinks daily for men could help lower your risk.
- Use tobacco. Long-term smokers are more likely to get this cancer than nonsmokers.
Which Treatments are Best for You?
Although, Van Der Beek has chosen to keep the details of his colon cancer journey and treatment process private, it’s important to understand that your doctor has many ways to treat colon cancer, depending on what stage the cancer is, including:
- Surgery
- Radiation therapy
- Chemotherapy
- Targeted therapy
- Immunotherapy
Surgery
Surgery is the main treatment for most early-stage colon cancers, according to the doctors SurvivorNet spoke with. The surgeon will remove the part of the colon or rectum where there is cancer, along with a small area of healthy tissue around it. Taking out as much of the cancer as possible is important for improving your outcome.
The surgery may be performed through small incisions (laparoscopy), or through a larger incision. Some people may need to wear a special bag (ostomy) to collect wastes after surgery.
Radiation Therapy
This treatment aims high-energy x-rays at the cancer to destroy the abnormal cells. The radiation can come from a machine outside your body, or be placed directly inside your body. Sometimes people get radiation before surgery, to shrink the tumor and make it easier for the surgeon to remove. This is called neoadjuvant radiation.
Chemotherapy
This treatment uses strong medicine to stop cancer cells from dividing, no matter where they are in your body. You may get a combination of chemotherapy drugs as your first treatment. Chemotherapy has been very well studied for colorectal cancer, and it is known to improve survival.
The most common therapy is a combination of chemo drugs called FOLFOX:
- FOL = leucovorin calcium (folinic acid)
- F = fluorouracil
- OX = oxaliplatin
Your doctor may add medications like irinotecan (FOLFIRI) or cetuximab, depending on how well your tumor shrinks with treatment and other specifics about your particular cancer. For FOLFOX, the medications are given through the vein and require regular doctor visits.
To determine exactly which chemotherapy regimen you get, your doctor will consider your age and how well you might tolerate the side effects of chemotherapy. Gene mutations (for example, BRAF and KRAS) and the location of the primary colon tumor also factor into the decision.
You can also get chemotherapy before colon cancer surgery, which is called neoadjuvant chemotherapy. Getting chemo first helps to shrink the tumor, which can make both the surgery and recovery easier, according to SurvivorNet’s experts. Chemo is also a treatment for cancer that returns after therapy.
Targeted Therapy
This treatment targets substances like proteins or genes that the cancer needs to grow. This makes targeted therapy more precise than chemotherapy, and less likely to damage healthy cells. One example of targeted therapy is bevacizumab (Avastin), which stops the growth of new blood vessels that feed tumors. Another group of targeted therapies are called epidermal growth factor receptor (EGFR) inhibitors, which block the cancer from growing.
Immunotherapy
This treatment makes your own immune system a more efficient cancer fighter. A group of drugs called checkpoint inhibitors, which includes pembrolizumab (Keytruda) and nivolumab (Opdivo), work by preventing cancer cells from hiding from your immune system. Checkpoint inhibitors may extend the amount of time before the cancer spreads.
Dr. Paul Oberstein, on which treatments doctors use to turn stage 4 colon cancer into a chronic but manageable disease
Contributing: SurvivorNet Staff
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