Ovarian Cancer Clinical Trial
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
Summary
The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video. Before and after watching the video, participants will complete questionnaires in the clinic.
Eligibility Criteria
Inclusion Criteria:
Part I
Age ≥45 years
Scheduled visit with a nongynecologic surgeon
Female or assigned female at birth
Part II
Age ≥45 years
At least one in situ fallopian tube
No desire or plan to have children in the future
Average risk of developing ovarian cancer
° Note: Average risk patients are defined as patients with no known genetic risk factor for developing ovarian cancer. Patients who, after obtaining family history, are suspected to have a hereditary ovarian cancer syndrome but have not yet been tested, will be referred for genetic evaluation.
Planned nongynecologic, intraabdominal, or pelvic surgery
Deemed to be a suitable candidate by gynecologic surgeon and primary nongynecologic surgeon (for example, on the basis of surgical history and current malignancy status)
Approved and signed informed consent
Exclusion Criteria:
Part I
Not fluent in English
° If there is a non-english speaking participant who is a strong candidate and meets all other criteria for Part 2, they are able to go directly onto Part 2 without completing Part 1. (Please see additional details in section 4.1 and 7.0.)
Known inherited ovarian cancer susceptibility
Part II
Personal history of a gynecologic malignancy
Carrier of a hereditary breast or ovarian cancer variant (e.g., BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, MLH1, MSH2, MSH6, PMS2)
Suspicious ovarian, fallopian tube, or uterine lesion on preoperative imaging
Previous bilateral salpingectomy or bilateral salpingo-oophorectomy
Current pregnancy
Emergent procedure or emergency procedure that has to be completed within 24 hours where clinical consent occurs in the inpatient setting or where the patient's immediate well-being is in danger or condition may be life threatening
Primary surgeon anticipates that OS will add significant time (>30-40min) to the planned procedure.
Inability to access the pelvis (ex., patient prone/lateral position) during the planned procedure.
Known history of pelvic fibrosis or significant adhesions.
Procedures with palliative intent only
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There are 10 Locations for this study
Boston Massachusetts, 02115, United States More Info
Basking Ridge New Jersey, 07920, United States More Info
Middletown New Jersey, 07748, United States More Info
Montvale New Jersey, 07645, United States More Info
Commack New York, 11725, United States More Info
Harrison New York, 10604, United States More Info
New York New York, 10065, United States More Info
Uniondale New York, 11553, United States More Info
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